Research & Clinical Trials
Expanding Access to Advanced Cancer Care
At Hematology Oncology Associates of Fredericksburg, we are committed to providing our patients with access to the latest advancements in cancer and hematologic care. Through participation in carefully selected clinical trials, eligible patients may have the opportunity to receive innovative therapies that are not yet widely available. These research opportunities contribute to the advancement of medicine while offering additional treatment options for qualifying patients.
Our physicians and research team remain at the forefront of emerging therapies and are dedicated to helping patients understand whether participation in a clinical trial may be appropriate as part of their individualized treatment plan.
What Are Clinical Trials?
Clinical trials are carefully designed research studies that evaluate new medications, medical devices and treatment approaches to determine their safety and effectiveness. They are an essential part of the process that advances medical care and helps establish new standards of treatment.
Clinical trials may investigate whether a new therapy is more effective than existing treatments, offers fewer side effects or improves quality of life for patients. Every clinical trial conducted at HOAF is selected by our physicians and research staff based on its scientific merit and its potential to address the needs of our patients and the broader community.
Clinical research may focus on:
Who May Be Eligible for a Clinical Trial?
At Hematology Oncology Associates of Fredericksburg, we offer clinical trials for a variety of cancer diagnoses, including studies targeting specific genetic or molecular characteristics identified through diagnostic testing. These precision medicine trials may provide treatment options tailored to an individual’s disease. We also participate in supportive care studies designed to improve symptom management and quality of life during treatment.
Each clinical trial has specific eligibility criteria based on factors such as diagnosis, stage of disease, prior treatments and overall health. Our experienced research nurse coordinators work closely with patients and their physicians to determine whether a particular study is an appropriate option.
If you are interested in learning more about clinical trial opportunities at HOAF, please contact our Research Department at HOAFresearch@aoncology.com. Our team will be happy to discuss studies that may be available for your condition.
The Phases Of Clinical Trials
Before a new medication or medical device receives approval from the U.S. Food and Drug Administration (FDA), it undergoes a rigorous evaluation through multiple phases of clinical research. Each phase is designed to answer specific questions regarding safety, effectiveness and long-term outcomes.
Protecting Patient Safety
Patient safety is the highest priority in every clinical trial conducted at HOAF. Clinical research is governed by strict ethical, scientific and regulatory standards designed to protect the rights, safety and well-being of every participant. Throughout the process, our research team carefully monitors each patient’s care and remains available to answer questions and provide ongoing support.
Global Partnerships, Proven Experience
Over the years, HOAF has collaborated with top industry sponsors including:
This experience allows us to offer patients access to trials across a wide range of disease states, including: genitourinary (GU), colorectal, esophageal, lung, breast, lymphoma, melanoma, myeloma, as well as biomarker-specific therapies and supportive care studies.
Our Achievements in Clinical Research
HOAF’s Clinical Trials Department is recognized for its excellence and rapid execution, with accomplishments such as:
Our track record demonstrates our commitment to efficient, high-quality research while providing patients with safe and personalized care throughout the study process.
Dr. Christopher Vaughn Discusses Expanding Access to Cancer Clinical Trials
Hematology Oncology Associates of Fredericksburg is proud to highlight Dr. Christopher Vaughn‘s participation in a recent Onco’Zine interview exploring the importance of bringing advanced cancer clinical trials closer to home. The discussion examines how precision oncology, molecular testing and collaborations with organizations such as Caris Life Sciences are helping expand access to innovative treatment opportunities within community oncology practices. Dr. Vaughn shares insights into HOAF’s efforts to connect patients with appropriate clinical trials while reducing the need for long-distance travel. His participation reflects HOAF’s ongoing commitment to advancing cancer care and providing patients in Fredericksburg and surrounding Virginia communities with personalized treatment options close to home.
Current Clinical Trials
We currently have a variety of open trials for patients in need of innovative cancer therapies. Our team is here to guide you through eligibility, enrollment, and treatment, ensuring you have the support and information you need every step of the way.
Contact us today to learn more about available clinical trials and how participation may benefit your care, or explore our current trials below.
HOAF Means Hope
Where Healing Begins, Strength Prevails
At HOAF, we are dedicated to providing exceptional care for cancer and blood disorders to the Fredericksburg, Stafford, and surrounding communities. Our practice integrates advanced treatments with a personalized approach, delivering the highest quality care. As an independent practice, we focus on individualized attention, ensuring each patient receives compassionate, comprehensive care tailored to their unique needs. Our cutting-edge facility, equipped with an on-site pharmacy, offers convenience and a seamless treatment experience.

